4f20

X-ray diffraction
2.5Å resolution

Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-179561 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Clumping factor B Chain: A
Molecule details ›
Chain: A
Length: 363 amino acids
Theoretical weight: 39.88 KDa
Source organism: Staphylococcus aureus subsp. aureus MRSA252
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6GDH2 (Residues: 197-542; Coverage: 42%)
Gene names: SAR2709, clfB
Sequence domains:
Structure domains:
Dermokine Chain: Q
Molecule details ›
Chain: Q
Length: 13 amino acids
Theoretical weight: 1.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q6E0U4 (Residues: 251-262; Coverage: 3%)
Gene names: DMKN, UNQ729/PRO1411

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3121
Unit cell:
a: 70.088Å b: 70.088Å c: 175.76Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.224 0.27
Expression systems:
  • Escherichia coli
  • Not provided