Function and Biology Details
Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
CLOCK-BMAL1 transcription complex (preferred)
PDBe Complex ID:
PDB-CPX-126671 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Basic helix-loop-helix ARNT-like protein 1
Molecule details ›
Chain: B
Length: 387 amino acids
Theoretical weight: 44.19 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 387 amino acids
Theoretical weight: 44.19 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q9WTL8 (Residues: 69-280, 281-453; Coverage: 61%)
Sequence domains:
Structure domains:
Circadian locomoter output cycles protein kaput
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 42.08 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 361 amino acids
Theoretical weight: 42.08 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: O08785 (Residues: 26-384; Coverage: 42%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID, ALS BEAMLINE 8.2.1
Spacegroup:
P212121
Expression system: Spodoptera frugiperda
