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› 4fgm

X-ray diffraction
2.39Å resolution

Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis. Northeast Structural Genomics Consortium Target IlR60.

Released:
DOI: 10.2210/pdb4fgm/pdb
Model geometry
Fit model/data
PDB entry 4fgm coloured by chain, front view.
PDB entry 4fgm coloured by chain, side view.
PDB entry 4fgm coloured by chain, top view.
Source organism: Idiomarina loihiensis L2TR
Entry authors: Vorobiev S, Su M, Tong T, Kohan E, Wang D, Everett JK, Acton TB, Montelione GT, Tong L, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed: 
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide orarylamide. Xaa is preferably Ala, but may be most amino acids includingPro (slow action). When a terminal hydrophobic residue is followed by aprolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-177765 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopeptidase N family protein, contains PDZ domain Chain: A
Molecule details ›
Chain: A
Length: 597 amino acids
Theoretical weight: 68.53 KDa
Source organism: Idiomarina loihiensis L2TR
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5QTY1 (Residues: 1-589; Coverage: 100%)
Gene name: IL1258
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MAE 1 x MAE
Ligand ZN 1 x ZN
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6222
Unit cell:
a: 119.657Å b: 119.657Å c: 220.134Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.19 0.209
Expression system: Escherichia coli BL21(DE3)

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