› 4fnj

X-ray diffraction
1.95Å resolution

Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and structure determination of a CUG RNA helix

Released:
DOI: 10.2210/pdb4fnj/pdb
PDB entry 4fnj coloured by chain, front view.
PDB entry 4fnj coloured by chain, side view.
PDB entry 4fnj coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and determination of the structure of a CUG RNA helix.
Coonrod LA, Lohman JR, Berglund JA
Biochemistry 51 8330-7 (2012)
PMID: 23025897

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196807 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (35-MER) Chain: A
Molecule details ›
Chain: A
Length: 35 nucleotides
Theoretical weight: 11.25 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 5 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: R3
Unit cell:
a: 70.336Å b: 70.336Å c: 68.236Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.208 0.266
Expression system: Not provided

Quick links

Citations

7 review citations

RNA Structures as Mediators of Neurological Diseases and as Drug Targets.
Bernat et al. (2015)
6 more

13 mentions without citation

Structural studies of CNG repeats.
Kiliszek et al. (2014)
12 more