Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Tyrosine-protein kinase, receptor class II, conserved site
- Tyrosine-protein kinase, active site
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, catalytic domain
- Protein kinase domain
- Protein kinase-like domain superfamily
- Receptor Tyrosine Kinase
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
ALK tyrosine kinase receptor (preferred)
PDBe Complex ID:
PDB-CPX-193961 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ALK tyrosine kinase receptor
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 36.8 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Length: 327 amino acids
Theoretical weight: 36.8 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q9UM73 (Residues: 1084-1410; Coverage: 20%)
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
