4fq1

X-ray diffraction
3Å resolution

Crystal Structure of PGT121 Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213464 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 244 amino acids
Theoretical weight: 26.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 211 amino acids
Theoretical weight: 22.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 56.753Å b: 74.672Å c: 114.917Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.264
Expression system: Homo sapiens