› 4fqm

X-ray diffraction
3.45Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111016 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin Chains: A, C, E, G, I, K
Molecule details ›
Chains: A, C, E, G, I, K
Length: 347 amino acids
Theoretical weight: 37.7 KDa
Source organism: Influenza B virus (B/Brisbane/60/2008)
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: C0LT38 (Residues: 16-362; Coverage: 62%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chains: B, D, F, H, J, L
Molecule details ›
Chains: B, D, F, H, J, L
Length: 179 amino acids
Theoretical weight: 19.26 KDa
Source organism: Influenza B virus (B/Brisbane/60/2008)
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: C0LT38 (Residues: 363-538; Coverage: 32%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 17 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21212
Unit cell:
a: 138.69Å b: 242.54Å c: 135.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.257 0.268
Expression system: Spodoptera frugiperda

Quick links

Citations

118 review citations

Advances in the development of influenza virus vaccines.
Krammer et al. (2015)
117 more

28 mentions without citation

Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?
Neu et al. (2016)
27 more