4fqq

X-ray diffraction
2.42Å resolution

Crystal Structure of Germline Antibody PGT121-GL Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-179700 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, C, E, L
Molecule details ›
Chains: A, C, E, L
Length: 215 amino acids
Theoretical weight: 22.92 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8N355 (Residues: 20-234; Coverage: 99%)
Gene name: IGL@
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 244 amino acids
Theoretical weight: 26.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6GMX6 (Residues: 20-116, 117-118, 119-242; Coverage: 50%)
Gene name: IGH@
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 54.934Å b: 344.743Å c: 55.23Å
α: 90° β: 91.95° γ: 90°
R-values:
R R work R free
0.195 0.194 0.237
Expression system: Homo sapiens