› 4fs5

X-ray diffraction
1.3Å resolution

Crystal structure of the Z-DNA hexamer CGCGCG at 500 mM MgCl2

Released:
DOI: 10.2210/pdb4fs5/pdb
PDB entry 4fs5 coloured by chain, front view.
PDB entry 4fs5 coloured by chain, side view.
PDB entry 4fs5 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Direct interactions between Z-DNA and alkaline earth cations, discovered in the presence of high concentrations of MgCl2 and CaCl2.
Chatake T, Sunami T
J Inorg Biochem 124 15-25 (2013)
PMID: 23578858

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117512 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MG 10 x MG
Ligand CL 4 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P32
Unit cell:
a: 18.593Å b: 18.593Å c: 72.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.211 0.264
Expression system: Not provided

Quick links

Citations

2 review citations

C8-Guanine modifications: effect on Z-DNA formation and its role in cancer.
Vongsutilers et al. (2018)
1 more

3 mentions without citation

Interaction of Conazole Pesticides Epoxiconazole and Prothioconazole with Human and Bovine Serum Albumin Studied Using Spectroscopic Methods and Molecular Modeling.
Golianová et al. (2021)
2 more