› 4fvj

X-ray diffraction
2.69Å resolution

SPFH domain of the mouse stomatin (Crystal form 2)

Released:
DOI: 10.2210/pdb4fvj/pdb
PDB entry 4fvj coloured by chain, front view.
PDB entry 4fvj coloured by chain, side view.
PDB entry 4fvj coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand J, Smith ES, Schwefel D, Lapatsina L, Poole K, Omerbašić D, Kozlenkov A, Behlke J, Lewin GR, Daumke O
EMBO J 31 3635-46 (2012)
PMID: 22850675

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156942 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stomatin Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 133 amino acids
Theoretical weight: 14.5 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P54116 (Residues: 86-213; Coverage: 45%)
Gene names: Epb7.2, Epb72, Stom
Sequence domains: SPFH domain / Band 7 family
Structure domains: Band 7 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2
Unit cell:
a: 178.53Å b: 91.38Å c: 86.138Å
α: 90° β: 111.88° γ: 90°
R-values:
R R work R free
0.248 0.246 0.29
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Acid-sensing ion channels: trafficking and synaptic function.
Zha XM. (2013)
9 more

5 mentions without citation

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand et al. (2012)
4 more