4g6f

X-ray diffraction
2.1Å resolution

Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-211649 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
10E8 Heavy Chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 236 amino acids
Theoretical weight: 25.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
10E8 Light Chain Chains: D, L
Molecule details ›
Chains: D, L
Length: 215 amino acids
Theoretical weight: 22.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
gp41 MPER Peptide Chains: F, P
Molecule details ›
Chains: F, P
Length: 34 amino acids
Theoretical weight: 4.63 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 68.021Å b: 71.432Å c: 129.236Å
α: 90° β: 104.5° γ: 90°
R-values:
R R work R free
0.181 0.18 0.218
Expression systems:
  • Homo sapiens
  • Not provided