› 4gbt

X-ray diffraction
3.2Å resolution

Structural characterization of H-1 Parvovirus: comparison of infectious virions to replication defective particles

Released:
DOI: 10.2210/pdb4gbt/pdb
PDB entry 4gbt coloured by chain, front view.
PDB entry 4gbt coloured by chain, side view.
PDB entry 4gbt coloured by chain, top view.
Source organism: H-1 parvovirus
Primary publication:
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
Halder S, Nam HJ, Govindasamy L, Vogel M, Dinsart C, Salomé N, McKenna R, Agbandje-McKenna M
J Virol 87 5128-40 (2013)
PMID: 23449783

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136601 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 735 amino acids
Theoretical weight: 81.34 KDa
Source organism: H-1 parvovirus
UniProt:
  • Canonical: P03136 (Residues: 1-246, 247-734; Coverage: 100%)
Sequence domains:
Structure domains: Parvovirus coat protein VP1/VP2

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 255.2Å b: 350.1Å c: 272.1Å
α: 90° β: 90.12° γ: 90°
R-values:
R R work R free
0.256 0.256 0.259

Quick links

Citations

6 review citations

Oncolytic parvoviruses: from basic virology to clinical applications.
Marchini et al. (2015)
5 more

5 mentions without citation

Twenty-Five Years of Structural Parvovirology.
Mietzsch et al. (2019)
4 more