Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178821 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TNF receptor-associated factor 3
Molecule details ›
Chain: A
Length: 198 amino acids
Theoretical weight: 22.66 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: TRAF/meprin, MATH domain
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Length: 198 amino acids
Theoretical weight: 22.66 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q60803 (Residues: 376-567; Coverage: 34%)
Sequence domains: TRAF/meprin, MATH domain
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Mitochondrial antiviral-signaling protein
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.27 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 21 amino acids
Theoretical weight: 2.27 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: Q8VCF0 (Residues: 138-158; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRF BEAMLINE BL17U
Spacegroup:
P321
Expression systems:
- Escherichia coli
- Not provided
