› 4gma

X-ray diffraction
3.94Å resolution

Crystal structure of the adenosylcobalamin riboswitch

Released:
DOI: 10.2210/pdb4gma/pdb
PDB entry 4gma coloured by chain, front view.
PDB entry 4gma coloured by chain, side view.
PDB entry 4gma coloured by chain, top view.
Source organism: marine metagenome
Primary publication:
B12 cofactors directly stabilize an mRNA regulatory switch.
Johnson JE, Reyes FE, Polaski JT, Batey RT
Nature 492 133-7 (2012)
PMID: 23064232

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196811 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
Adenosylcobalamin riboswitch Chain: Z
Molecule details ›
Chain: Z
Length: 210 nucleotides
Theoretical weight: 68.27 KDa
Source organism: marine metagenome
Expression system: Not provided
Sequence domains: Cobalamin riboswitch

Ligands and Environments

1 bound ligand:
Ligand B1Z 1 x B1Z
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C222
Unit cell:
a: 96.648Å b: 243.545Å c: 87.102Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.262 0.262 0.275
Expression system: Not provided

Quick links

Citations

24 review citations

A decade of riboswitches.
Serganov et al. (2013)
23 more

21 mentions without citation

Long-Range Interactions in Riboswitch Control of Gene Expression.
Jones et al. (2017)
20 more