› 4gnj

X-ray diffraction
1.93Å resolution

Crystal Structure Analysis of Leishmania siamensis Triosephosphate Isomerase

Released:
DOI: 10.2210/pdb4gnj/pdb
PDB entry 4gnj coloured by chain, front view.
PDB entry 4gnj coloured by chain, side view.
PDB entry 4gnj coloured by chain, top view.
Source organism: Leishmania sp. 'siamensis'
Entry authors: Kuaprasert B, Riangrungroj P, Pornthanakasem W, Suginta W, Mungthin M, Leelayoova S, Leartsakulpanich U

Function and Biology Details

Reaction catalysed: 
D-glyceraldehyde 3-phosphate = glycerone phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Triosephosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 29.24 KDa
Source organism: Leishmania sp. 'siamensis'
Expression system: Escherichia coli
UniProt:
  • Canonical: I2APN2 (Residues: 1-251; Coverage: 100%)
Gene name: tim
Sequence domains: Triosephosphate isomerase
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
Ligand ARS 2 x ARS
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P2
Unit cell:
a: 39.58Å b: 78.79Å c: 83.16Å
α: 90° β: 101.15° γ: 90°
R-values:
R R work R free
0.154 0.151 0.199
Expression system: Escherichia coli

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