› 4gqt

X-ray diffraction
2.15Å resolution

N-terminal domain of C. elegans Hsp90

Released:
DOI: 10.2210/pdb4gqt/pdb
PDB entry 4gqt coloured by chain, front view.
PDB entry 4gqt coloured by chain, side view.
PDB entry 4gqt coloured by chain, top view.
Source organism: Caenorhabditis elegans
Entry authors: Osipiuk J, Chhor G, Gu M, Van Oosten-Hawle P, Morimoto RI, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172693 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock protein 90 Chains: A, B
Molecule details ›
Chains: A, B
Length: 227 amino acids
Theoretical weight: 25.42 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q18688 (Residues: 1-224; Coverage: 32%)
Gene names: C47E8.5, daf-21
Sequence domains: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Structure domains: Histidine kinase-like ATPase, C-terminal domain

Ligands and Environments

2 bound ligands:
Ligand ADP 2 x ADP
Ligand ZN 10 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P212121
Unit cell:
a: 39.652Å b: 86.658Å c: 128.67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.194 0.252
Expression system: Escherichia coli BL21(DE3)

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