› 4grf

X-ray diffraction
1.76Å resolution

Crystal structure of thioredoxin domain of thiol-disulfide oxidoreductase BVU-2223 (Target EFI-501010) from Bacteroides vulgatus

Released:
DOI: 10.2210/pdb4grf/pdb
PDB entry 4grf coloured by chain, front view.
PDB entry 4grf coloured by chain, side view.
PDB entry 4grf coloured by chain, top view.
Source organism: Phocaeicola vulgatus ATCC 8482
Entry authors: Patskovsky Y, Sampathkumar P, Toro R, Bhosle R, Zencheck WD, Hillerich B, Seidel RD, Washington E, Scott Glenn A, Chowdhury S, Evans B, Imker HJ, Hammonds J, Al-Obaidi NF, Stead M, Love J, Armstrong RN, Gerlt JA, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107879 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 17.36 KDa
Source organism: Phocaeicola vulgatus ATCC 8482
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A6L2G9 (Residues: 252-392; Coverage: 36%)
Gene name: BVU_2223
Sequence domains: AhpC/TSA family
Structure domains: Glutaredoxin

Ligands and Environments

3 bound ligands:
Ligand CL 5 x CL
Ligand SO4 1 x SO4
Ligand GSH 1 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 34.664Å b: 52.65Å c: 82.622Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.165 0.21
Expression system: Escherichia coli BL21(DE3)

Quick links