4gxb

X-ray diffraction
1.8Å resolution

Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-169521 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Sorting nexin-17 Chain: A
Molecule details ›
Chain: A
Length: 280 amino acids
Theoretical weight: 31.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15036 (Residues: 111-388; Coverage: 59%)
Gene names: KIAA0064, SNX17
Sequence domains:
Structure domains:
P-selectin Chain: B
Molecule details ›
Chain: B
Length: 41 amino acids
Theoretical weight: 4.32 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01102 (Residues: 735-768; Coverage: 5%)
Gene names: Grmp, Selp

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P3121
Unit cell:
a: 93.754Å b: 93.754Å c: 91.308Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.177 0.204
Expression system: Escherichia coli