› 4gxy

X-ray diffraction
3.05Å resolution

RNA structure

Released:
DOI: 10.2210/pdb4gxy/pdb
PDB entry 4gxy coloured by chain, front view.
PDB entry 4gxy coloured by chain, side view.
PDB entry 4gxy coloured by chain, top view.
Source organism: Symbiobacterium thermophilum
Primary publication:
Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch.
Peselis A, Serganov A
Nat Struct Mol Biol 19 1182-4 (2012)
PMID: 23064646

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195855 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
Adenosylcobalamin riboswitch Chain: A
Molecule details ›
Chain: A
Length: 172 nucleotides
Theoretical weight: 56.19 KDa
Source organism: Symbiobacterium thermophilum
Expression system: Not provided
Sequence domains: Cobalamin riboswitch

Ligands and Environments

3 bound ligands:
Ligand B1Z 2 x B1Z
Ligand IRI 7 x IRI
Ligand MG 2 x MG
2 modified residues:
Ligand GTP 1 x GTP
Ligand CCC 1 x CCC

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P3121
Unit cell:
a: 96.633Å b: 96.633Å c: 132.684Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.208 0.25
Expression system: Not provided

Quick links

Citations

8 review citations

A decade of riboswitches.
Serganov et al. (2013)
7 more

26 mentions without citation

Structure and function of the T-loop structural motif in noncoding RNAs.
Chan et al. (2013)
25 more