› 4gzc

X-ray diffraction
1.3Å resolution

Crystal structure of yeast Ent2 ENTH domain

Released:
DOI: 10.2210/pdb4gzc/pdb
PDB entry 4gzc coloured by chain, front view.
PDB entry 4gzc coloured by chain, side view.
PDB entry 4gzc coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Crystallographic analysis of the ENTH domain from yeast epsin Ent2 that induces a cell division phenotype.
Costakes GT, Sen A, Aguilar RC, Stauffacher CV
Protein Sci 22 755-61 (2013)
PMID: 23553749

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170246 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epsin-2 Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 21.02 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05785 (Residues: 1-149; Coverage: 24%)
Gene names: ENT2, YLR206W
Sequence domains: ENTH domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 41.31Å b: 53.35Å c: 70.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.212 0.231
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae.
Roelants et al. (2017)

3 mentions without citation

Epsin and Sla2 form assemblies through phospholipid interfaces.
Garcia-Alai et al. (2018)
2 more