› 4h5f

X-ray diffraction
1.9Å resolution

Crystal structure of an amino acid ABC transporter substrate-binding protein from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine, form 1

Released:
DOI: 10.2210/pdb4h5f/pdb
Model geometry
Fit model/data
PDB entry 4h5f coloured by chain, front view.
PDB entry 4h5f coloured by chain, side view.
PDB entry 4h5f coloured by chain, top view.
Source organism: Streptococcus pneumoniae str. Canada MDR_19A
Entry authors: Stogios PJ, Wawrzak Z, Kudritska M, Minasov G, Yim V, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amino acid ABC superfamily ATP binding cassette transporter, binding protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 243 amino acids
Theoretical weight: 26.18 KDa
Source organism: Streptococcus pneumoniae str. Canada MDR_19A
Expression system: Escherichia coli BL21(DE3)
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

8 bound ligands:
Ligand SO4 5 x SO4
Ligand CL 1 x CL
Ligand PEG 19 x PEG
Ligand GOL 6 x GOL
Ligand PGE 4 x PGE
Ligand ARG 4 x ARG
Ligand ACT 7 x ACT
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P21
Unit cell:
a: 99.373Å b: 61.705Å c: 103.626Å
α: 90° β: 118.04° γ: 90°
R-values:
R R work R free
0.166 0.164 0.2
Expression system: Escherichia coli BL21(DE3)

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