› 4h6v

X-ray diffraction
1.7Å resolution

Structure of Patellamide maturation protease PatA

Released:
DOI: 10.2210/pdb4h6v/pdb
PDB entry 4h6v coloured by chain, front view.
PDB entry 4h6v coloured by chain, side view.
PDB entry 4h6v coloured by chain, top view.
Source organism: Prochloron didemni
Primary publication:
Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Agarwal V, Pierce E, McIntosh J, Schmidt EW, Nair SK
Chem Biol 19 1411-22 (2012)
PMID: 23177196

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176028 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Subtilisin-like protein Chain: A
Molecule details ›
Chain: A
Length: 306 amino acids
Theoretical weight: 32.02 KDa
Source organism: Prochloron didemni
Expression system: Escherichia coli
UniProt:
  • Canonical: Q52QI9 (Residues: 1-303; Coverage: 43%)
Gene name: patA
Sequence domains: Subtilase family
Structure domains: Peptidase S8/S53 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P41
Unit cell:
a: 83.717Å b: 83.717Å c: 42.27Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.244
Expression system: Escherichia coli

Quick links

Citations

12 review citations

New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.
Ortega et al. (2016)
11 more

4 mentions without citation

Mechanisms of cyanobactin biosynthesis.
Czekster et al. (2016)
3 more