Function and Biology Details
Reaction catalysed:
ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- GHMP kinase, C-terminal domain superfamily
- Mevalonate kinase
- GHMP kinase, C-terminal domain
- GHMP kinase, ATP-binding, conserved site
- GHMP kinase N-terminal domain
- Mevalonate kinase, archaeal
- Ribosomal protein uS5 domain 2-type superfamily
- Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Mevalonate kinase (preferred)
PDBe Complex ID:
PDB-CPX-185812 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mevalonate kinase
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 33.8 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 321 amino acids
Theoretical weight: 33.8 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q8PW39 (Residues: 1-301; Coverage: 100%)
Sequence domains:
Structure domains:
Mevalonate kinase
Molecule details ›
Chain: B
Length: 321 amino acids
Theoretical weight: 33.85 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 321 amino acids
Theoretical weight: 33.85 KDa
Source organism: Methanosarcina mazei Go1
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q8PW39 (Residues: 1-301; Coverage: 100%)
Sequence domains:
Structure domains:
