4han

X-ray diffraction
2.55Å resolution

Crystal structure of Galectin 8 with NDP52 peptide

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-126163 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Galectin-8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 293 amino acids
Theoretical weight: 33.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00214 (Residues: 1-155, 184-317; Coverage: 91%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls
Calcium-binding and coiled-coil domain-containing protein 2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 14 amino acids
Theoretical weight: 1.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13137 (Residues: 372-385; Coverage: 3%)
Gene names: CALCOCO2, NDP52

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P3112
Unit cell:
a: 71.884Å b: 71.884Å c: 314.493Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.191 0.214
Expression system: Escherichia coli