› 4has

X-ray diffraction
1.74Å resolution

Crystal structure of PX domain of human sorting nexin SNX27

Released:
DOI: 10.2210/pdb4has/pdb
PDB entry 4has coloured by chain, front view.
PDB entry 4has coloured by chain, side view.
PDB entry 4has coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Froese DS, Krojer T, Strain-Damerell C, Allerston C, Kiyani W, Burgess-Brown N, von Delft F, Arrowsmith C, Bountra C, Edwards A, Yue WW, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188608 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-27 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 15.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96L92 (Residues: 156-265; Coverage: 20%)
Gene names: KIAA0488, My014, SNX27
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

2 bound ligands:
Ligand CIT 1 x CIT
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P212121
Unit cell:
a: 47.58Å b: 47.82Å c: 96.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.204
Expression system: Escherichia coli

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