› 4hnm

X-ray diffraction
2.9Å resolution

Crystal structure of human catenin-beta-like 1 56 kDa fragment

Released:
DOI: 10.2210/pdb4hnm/pdb
PDB entry 4hnm coloured by chain, front view.
PDB entry 4hnm coloured by chain, side view.
PDB entry 4hnm coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family.
Huang X, Wang G, Wu Y, Du Z
Acta Crystallogr D Biol Crystallogr 69 1598-608 (2013)
PMID: 23897482

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186796 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-catenin-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 489 amino acids
Theoretical weight: 57.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WYA6 (Residues: 75-563; Coverage: 87%)
Gene names: C20orf33, CTNNBL1, PP8304
Sequence domains: Catenin-beta-like, Arm-motif containing nuclear
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 19 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-E
Spacegroup: P41212
Unit cell:
a: 94.97Å b: 94.97Å c: 172.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.207 0.258
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 citation in other articles

An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses.
Wang et al. (2020)
6 more