Function and Biology Details
Reaction catalysed:
(1a) 2 L-arginine + 2 NADPH + 2 O(2) = 2 N(omega)-hydroxy-L-arginine + 2 NADP(+) + 2 H(2)O
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Alpha-1-syntrophin and Nitric oxide synthase 1 (preferred)
PDBe Complex ID:
PDB-CPX-151519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-1-syntrophin
Molecule details ›
Chains: A, C, E
Length: 88 amino acids
Theoretical weight: 9.39 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Length: 88 amino acids
Theoretical weight: 9.39 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q61234 (Residues: 77-162; Coverage: 17%)
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Nitric oxide synthase 1
Molecule details ›
Chains: B, D, F
Length: 123 amino acids
Theoretical weight: 13.29 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Length: 123 amino acids
Theoretical weight: 13.29 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P29476 (Residues: 4-126; Coverage: 9%)
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.3.1
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
