› 4hp4

X-ray diffraction
2Å resolution

Crystal structure of PAS domain from the fruit-fly ELK potassium channel

Released:
DOI: 10.2210/pdb4hp4/pdb
PDB entry 4hp4 coloured by chain, front view.
PDB entry 4hp4 coloured by chain, side view.
PDB entry 4hp4 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural properties of PAS domains from the KCNH potassium channels.
Adaixo R, Harley CA, Castro-Rodrigues AF, Morais-Cabral JH
PLoS One 8 e59265 (2013)
PMID: 23555008

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106796 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eag-like K[+] channel, isoform A Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 15.12 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: A1ZB14 (Residues: 11-136; Coverage: 10%)
Gene names: CG5076, Dmel\CG5076, Dmel_CG5076, Elk, dmELK, elk
Sequence domains: PAS domain
Structure domains: PAS domain

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand GOL 1 x GOL
1 modified residue:
Ligand MLY 24 x MLY

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P4132
Unit cell:
a: 150.306Å b: 150.306Å c: 150.306Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.173 0.191
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Kv10.1 K(+) channel: from physiology to cancer.
Ouadid-Ahidouch et al. (2016)
11 more

3 mentions without citation

Structural properties of PAS domains from the KCNH potassium channels.
Adaixo et al. (2013)
2 more