› 4hqm

X-ray diffraction
2.55Å resolution

The crystal structure of QsrR-menadione complex

Released:
DOI: 10.2210/pdb4hqm/pdb
PDB entry 4hqm coloured by chain, front view.
PDB entry 4hqm coloured by chain, side view.
PDB entry 4hqm coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Ji Q, Zhang L, Jones MB, Sun F, Deng X, Liang H, Cho H, Brugarolas P, Gao YN, Peterson SN, Lan L, Bae T, He C
Proc Natl Acad Sci U S A 110 5010-5 (2013)
PMID: 23479646

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164552 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
QsrR protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 115 amino acids
Theoretical weight: 13.07 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand 17Z 2 x 17Z
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P6
Unit cell:
a: 124.758Å b: 124.758Å c: 30.633Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.285 0.284 0.296
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Thiol-based redox switches in prokaryotes.
Hillion et al. (2015)
4 more

5 mentions without citation

Metallochaperones and metalloregulation in bacteria.
Capdevila et al. (2017)
4 more