› 4hr6

X-ray diffraction
2.25Å resolution

Crystal structure of snake gourd (Trichosanthes anguina) seed lectin, a three chain homologue of type II RIPs

Released:
DOI: 10.2210/pdb4hr6/pdb
Model geometry
Fit model/data
PDB entry 4hr6 coloured by chain, front view.
PDB entry 4hr6 coloured by chain, side view.
PDB entry 4hr6 coloured by chain, top view.
Source organism: Trichosanthes anguina
Primary publication:
The sequence and structure of snake gourd (Trichosanthes anguina) seed lectin, a three-chain nontoxic homologue of type II RIPs.
Sharma A, Pohlentz G, Bobbili KB, Jeyaprakash AA, Chandran T, Mormann M, Swamy MJ, Vijayan M
Acta Crystallogr D Biol Crystallogr 69 1493-503 (2013)
PMID: 23897472

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197539 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Lectin Chain: A
Molecule details ›
Chain: A
Length: 41 amino acids
Theoretical weight: 4.65 KDa
Source organism: Trichosanthes anguina
UniProt:
  • Canonical: U3KRF6 (Residues: 1-41; Coverage: 100%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Seed lectin Abeta chain Chain: B
Molecule details ›
Chain: B
Length: 206 amino acids
Theoretical weight: 23.13 KDa
Source organism: Trichosanthes anguina
UniProt:
  • Canonical: U3KRF8 (Residues: 48-253; Coverage: 40%)
Structure domains:
Seed lectin B chain Chain: C

Ligands and Environments

1 bound ligand:
Ligand AMG 2 x AMG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P6122
Unit cell:
a: 102.081Å b: 102.081Å c: 271.64Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.187 0.229

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Citations

1 review citation

Ribosome-inactivating and related proteins.
Schrot et al. (2015)
7 other articles