› 4huc

X-ray diffraction
1.86Å resolution

Crystal structure of LdtMt2, a L,D-transpeptidase from Mycobacterium tuberculosis: domain B and C

Released:
DOI: 10.2210/pdb4huc/pdb
PDB entry 4huc coloured by chain, front view.
PDB entry 4huc coloured by chain, side view.
PDB entry 4huc coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis.
Böth D, Steiner EM, Stadler D, Lindqvist Y, Schnell R, Schneider G
Acta Crystallogr D Biol Crystallogr 69 432-41 (2013)
PMID: 23519418

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129428 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L,D-transpeptidase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 262 amino acids
Theoretical weight: 28.51 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O53223 (Residues: 149-408; Coverage: 70%)
Gene names: MT2594, V735_02606, ldtB
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ACT 12 x ACT
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: I212121
Unit cell:
a: 116.027Å b: 121.43Å c: 123.298Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.188
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Peptidoglycan remodeling by the coordinated action of multispecific enzymes.
Alvarez et al. (2014)
2 more

4 mentions without citation

Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis.
Böth et al. (2013)
3 more