› 4i0n

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108793 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocidin/Hemolysin toxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 289 amino acids
Theoretical weight: 32.86 KDa
Source organism: Clostridium perfringens
Expression system: Escherichia coli
UniProt:
  • Canonical: A8ULG6 (Residues: 34-322; Coverage: 99%)
Gene name: netB
Sequence domains: Leukocidin/Hemolysin toxin family
Structure domains: Leukocidin/porin MspA

Ligands and Environments

2 bound ligands:
Ligand MG 5 x MG
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: C2
Unit cell:
a: 167.444Å b: 29.698Å c: 56.265Å
α: 90° β: 99.09° γ: 90°
R-values:
R R work R free
0.17 0.168 0.205
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease.
Uzal et al. (2014)
14 more

1 mention without citation

Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens.
Yan et al. (2013)