› 4i1t

X-ray diffraction
2.8Å resolution

Crystal structure of the cap-snatching endonuclease from Pichinde virus

Released:
DOI: 10.2210/pdb4i1t/pdb
PDB entry 4i1t coloured by chain, front view.
PDB entry 4i1t coloured by chain, side view.
PDB entry 4i1t coloured by chain, top view.
Source organism: Mammarenavirus caliense
Entry authors: Bussetta C, Choi KH

Function and Biology Details

Reaction catalysed: 
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187492 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-directed RNA polymerase L Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 25.14 KDa
Source organism: Mammarenavirus caliense
Expression system: Escherichia coli
UniProt:
  • Canonical: Q915A5 (Residues: 1-194; Coverage: 9%)
Gene name: L
Sequence domains: Arenavirus cap snatching domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6422
Unit cell:
a: 142.962Å b: 142.962Å c: 46.835Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.239 0.236 0.294
Expression system: Escherichia coli

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