4i43

X-ray diffraction
2Å resolution

Crystal structure of Prp8:Aar2 complex

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-152275 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
A1 cistron-splicing factor AAR2 Chain: A
Molecule details ›
Chain: A
Length: 384 amino acids
Theoretical weight: 44.97 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32357 (Residues: 1-355; Coverage: 100%)
Gene names: AAR2, YBL06.06, YBL0611, YBL074C
Sequence domains:
Structure domains:
Pre-mRNA-splicing factor 8 Chain: B
Molecule details ›
Chain: B
Length: 1564 amino acids
Theoretical weight: 180.22 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P33334 (Residues: 885-2413; Coverage: 63%)
Gene names: DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2221
Unit cell:
a: 118.856Å b: 158.595Å c: 220.507Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.249
Expression system: Saccharomyces cerevisiae