› 4i83

X-ray diffraction
2.6Å resolution

Crystal Structure of (3R)-Hydroxymyristoyl-ACP Dehydratase from Neisseria meningitidis FAM18

Released:
DOI: 10.2210/pdb4i83/pdb
PDB entry 4i83 coloured by chain, front view.
PDB entry 4i83 coloured by chain, side view.
PDB entry 4i83 coloured by chain, top view.
Source organism: Neisseria meningitidis FAM18
Entry authors: Khandokar YB, Forwood JK

Function and Biology Details

Reaction catalysed: 
A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106643 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 152 amino acids
Theoretical weight: 16.9 KDa
Source organism: Neisseria meningitidis FAM18
Expression system: Escherichia coli
UniProt:
  • Canonical: A1KRL1 (Residues: 1-149; Coverage: 100%)
Gene names: NMC0170, fabZ
Sequence domains: FabA-like domain
Structure domains: Hotdog Thioesterase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 72.44Å b: 103.98Å c: 135.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.224 0.256
Expression system: Escherichia coli

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