Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Tyrosine-specific protein phosphatase, PTPase domain
- Protein-tyrosine phosphatase-like
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
- Protein-tyrosine phosphatase, non-receptor type-1/2
- Rossmann-like alpha/beta/alpha sandwich fold
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein phosphatase non-receptor type 1 (preferred)
PDBe Complex ID:
PDB-CPX-148259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 1
Molecule details ›
Chain: A
Length: 354 amino acids
Theoretical weight: 40.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily
Length: 354 amino acids
Theoretical weight: 40.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P18031 (Residues: 1-320; Coverage: 74%)
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily
