› 4idn

X-ray diffraction
2.25Å resolution

Human atlastin-1 1-446, C-his6, GppNHp

Released:
DOI: 10.2210/pdb4idn/pdb
PDB entry 4idn coloured by chain, front view.
PDB entry 4idn coloured by chain, side view.
PDB entry 4idn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Byrnes LJ, Singh A, Szeto K, Benvin NM, O'Donnell JP, Zipfel WR, Sondermann H
EMBO J 32 369-84 (2013)
PMID: 23334294

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186779 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Atlastin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 457 amino acids
Theoretical weight: 52.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8WXF7 (Residues: 1-446; Coverage: 80%)
Gene names: ATL1, GBP3, SPG3A
Sequence domains: Guanylate-binding protein, N-terminal domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand GNP 2 x GNP
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 49.688Å b: 115.78Å c: 181.127Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.218
Expression system: Escherichia coli BL21

Quick links

Citations

14 review citations

Form follows function: the importance of endoplasmic reticulum shape.
Westrate et al. (2015)
13 more

2 mentions without citation

Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Byrnes et al. (2013)
1 more