› 4ihk

X-ray diffraction
1.2Å resolution

Crystal structure of the Collagen VI alpha3 N5 domain R1061Q

Released:
DOI: 10.2210/pdb4ihk/pdb
PDB entry 4ihk coloured by chain, front view.
PDB entry 4ihk coloured by chain, side view.
PDB entry 4ihk coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein.
Becker AK, Mikolajek H, Paulsson M, Wagener R, Werner JM
Structure 22 199-208 (2014)
PMID: 24332716

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123205 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen, type VI, alpha 3 Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 21.68 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: E9PWQ3 (Residues: 1022-1224; Coverage: 6%)
Gene name: Col6a3
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P43212
Unit cell:
a: 55.07Å b: 55.07Å c: 106.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.14 0.139 0.166
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Collagen-mediated hemostasis.
Manon-Jensen et al. (2016)
1 more

1 mention without citation

New COL6A6 Variant Causes Autosomal Dominant Retinitis Pigmentosa in a Four-Generation Family.
Vaclavik et al. (2022)