› 4ijk

X-ray diffraction
2.54Å resolution

Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695

Released:
DOI: 10.2210/pdb4ijk/pdb
PDB entry 4ijk coloured by chain, front view.
PDB entry 4ijk coloured by chain, side view.
PDB entry 4ijk coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Entry authors: Hou J, Osinski T, Zheng H, Shumilin I, Shabalin IG, Shatsman S, Anderson WF, Minor W, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127740 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 271 amino acids
Theoretical weight: 29.44 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O25286 (Residues: 1-247; Coverage: 100%)
Gene name: HP_0561
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21212
Unit cell:
a: 127.168Å b: 114.642Å c: 69.501Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.235 0.272
Expression system: Escherichia coli BL21(DE3)

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