› 4io1

X-ray diffraction
1.65Å resolution

Crystal structure of ribose-5-isomerase A from Francisella Tularensis

Released:
DOI: 10.2210/pdb4io1/pdb
PDB entry 4io1 coloured by chain, front view.
PDB entry 4io1 coloured by chain, side view.
PDB entry 4io1 coloured by chain, top view.
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Entry authors: Rostankowski R, Nakka C, Grimshaw S, Borek D, Otwinowski Z, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
D-ribose 5-phosphate = D-ribulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177667 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribose-5-phosphate isomerase A Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 24.49 KDa
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5NFM5 (Residues: 1-224; Coverage: 100%)
Gene names: FTT_1208, rpiA
Sequence domains: Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand CL 6 x CL
Ligand BR 2 x BR
Ligand PO4 3 x PO4
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 36.281Å b: 85.765Å c: 70.634Å
α: 90° β: 94.52° γ: 90°
R-values:
R R work R free
0.15 0.148 0.182
Expression system: Escherichia coli BL21(DE3)

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