› 4io2

X-ray diffraction
1.37Å resolution

Crystal Structure of the AvGluR1 ligand binding domain complex with glutamate at 1.37 Angstrom resolution

Released:
DOI: 10.2210/pdb4io2/pdb
PDB entry 4io2 coloured by chain, front view.
PDB entry 4io2 coloured by chain, side view.
PDB entry 4io2 coloured by chain, top view.
Source organism: Adineta vaga
Primary publication:
Anions mediate ligand binding in Adineta vaga glutamate receptor ion channels.
Lomash S, Chittori S, Brown P, Mayer ML
Structure 21 414-25 (2013)
PMID: 23434404

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123192 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ionotropic glutamate receptor C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 248 amino acids
Theoretical weight: 27.49 KDa
Source organism: Adineta vaga
Expression system: Escherichia coli
UniProt:
  • Canonical: E9P5T5 (Residues: 457-567, 591-812; Coverage: 28%)
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand CL 4 x CL
Ligand GLU 2 x GLU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 55.37Å b: 101.052Å c: 56.744Å
α: 90° β: 116.46° γ: 90°
R-values:
R R work R free
0.138 0.137 0.169
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
5 other articles

3 mentions without citation

The structural bases for agonist diversity in an Arabidopsis thaliana glutamate receptor-like channel.
Alfieri et al. (2020)
2 more