› 4io5

X-ray diffraction
1.72Å resolution

Crystal Structure of the AvGluR1 ligand binding domain complex with alanine at 1.72 Angstrom resolution

Released:
DOI: 10.2210/pdb4io5/pdb
PDB entry 4io5 coloured by chain, front view.
PDB entry 4io5 coloured by chain, side view.
PDB entry 4io5 coloured by chain, top view.
Source organism: Adineta vaga
Primary publication:
Anions mediate ligand binding in Adineta vaga glutamate receptor ion channels.
Lomash S, Chittori S, Brown P, Mayer ML
Structure 21 414-25 (2013)
PMID: 23434404

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123192 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ionotropic glutamate receptor C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 248 amino acids
Theoretical weight: 27.49 KDa
Source organism: Adineta vaga
Expression system: Escherichia coli
UniProt:
  • Canonical: E9P5T5 (Residues: 457-567, 591-812; Coverage: 28%)
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand ALA 2 x ALA
Ligand CL 6 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 55.428Å b: 100.691Å c: 56.655Å
α: 90° β: 116.44° γ: 90°
R-values:
R R work R free
0.16 0.158 0.195
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
7 other articles

1 mention without citation

Anions mediate ligand binding in Adineta vaga glutamate receptor ion channels.
Lomash et al. (2013)