4iqy

X-ray diffraction
1.55Å resolution

Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-106766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribose glycohydrolase MACROD2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 240 amino acids
Theoretical weight: 27.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A1Z1Q3 (Residues: 7-243; Coverage: 56%)
Gene names: C20orf133, MACROD2
Sequence domains: Macro domain
Structure domains: Leucine Aminopeptidase, subunit E, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P1
Unit cell:
a: 40.713Å b: 49.883Å c: 66.972Å
α: 69.82° β: 72.35° γ: 86.08°
R-values:
R R work R free
0.16 0.158 0.187
Expression system: Escherichia coli