› 4iry

X-ray diffraction
2.8Å resolution

Influenza A virus tail-loop free nucleoprotein at 2.8 A resolution

Released:
DOI: 10.2210/pdb4iry/pdb
PDB entry 4iry coloured by chain, front view.
PDB entry 4iry coloured by chain, side view.
PDB entry 4iry coloured by chain, top view.
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
Primary publication:
Biochemical and structural evidence in support of a coherent model for the formation of the double-helical influenza A virus ribonucleoprotein.
Ye Q, Guu TS, Mata DA, Kuo RL, Smith B, Krug RM, Tao YJ
mBio 4 e00467-12 (2012)
PMID: 23269829

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172920 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 483 amino acids
Theoretical weight: 54.75 KDa
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: Q1K9H2 (Residues: 1-401, 430-498; Coverage: 94%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: C2
Unit cell:
a: 60.183Å b: 155.618Å c: 97.774Å
α: 90° β: 90.94° γ: 90°
R-values:
R R work R free
0.242 0.242 0.298
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Antiviral strategies against influenza virus: towards new therapeutic approaches.
Loregian et al. (2014)
7 more

3 mentions without citation

Predicting evolutionary site variability from structure in viral proteins: buriedness, packing, flexibility, and design.
Shahmoradi et al. (2014)
2 more