› 4izo

X-ray diffraction
1.85Å resolution

Crystal structure of kinase Phosphoribosylaminoimidazole carboxylase, ATPase subunit from Burkholderia thailandensis

Released:
DOI: 10.2210/pdb4izo/pdb
PDB entry 4izo coloured by chain, front view.
PDB entry 4izo coloured by chain, side view.
PDB entry 4izo coloured by chain, top view.
Source organism: Burkholderia thailandensis E264
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173998 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N5-carboxyaminoimidazole ribonucleotide synthase Chain: A
Molecule details ›
Chain: A
Length: 419 amino acids
Theoretical weight: 43.79 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2T0S5 (Residues: 1-398; Coverage: 100%)
Gene names: BTH_I0668, purK
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P6122
Unit cell:
a: 53.93Å b: 53.93Å c: 465.92Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.184 0.182 0.214
Expression system: Escherichia coli BL21(DE3)

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