› 4j0u

X-ray diffraction
1.97Å resolution

Crystal structure of IFIT5/ISG58

Released:
DOI: 10.2210/pdb4j0u/pdb
PDB entry 4j0u coloured by chain, front view.
PDB entry 4j0u coloured by chain, side view.
PDB entry 4j0u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Liu Y, Liang H, Feng F, Yuan L, Wang YE, Crowley C, Lv Z, Li J, Zeng S, Cheng G

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171638 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced protein with tetratricopeptide repeats 5 Chain: A
Molecule details ›
Chain: A
Length: 482 amino acids
Theoretical weight: 55.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13325 (Residues: 1-482; Coverage: 100%)
Gene names: IFIT5, ISG58, RI58
Sequence domains:
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U, DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 63.722Å b: 71.529Å c: 115.527Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.193 0.236
Expression system: Escherichia coli

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