Function and Biology Details
Reaction catalysed:
Hydrolysis of -Gln(76)-|-Phe- bond in synaptobrevin (also known as neuronal vesicle-associated membrane protein, VAMP).
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tetanus toxin heavy chain (preferred)
PDBe Complex ID:
PDB-CPX-138291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetanus toxin light chain
Molecule details ›
Chain: A
Length: 426 amino acids
Theoretical weight: 49.06 KDa
Source organism: Clostridium tetani E88
Expression system: Escherichia coli
UniProt:
Sequence domains: Clostridial neurotoxin zinc protease
Structure domains: Metalloproteases ("zincins"), catalytic domain like
Length: 426 amino acids
Theoretical weight: 49.06 KDa
Source organism: Clostridium tetani E88
Expression system: Escherichia coli
UniProt:
- Canonical:
P04958 (Residues: 2-427; Coverage: 32%)
Sequence domains: Clostridial neurotoxin zinc protease
Structure domains: Metalloproteases ("zincins"), catalytic domain like
