Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189323 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MOB kinase activator 1A
Molecule details ›
Chains: A, C
Length: 184 amino acids
Theoretical weight: 21.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Mob1/phocein family
Structure domains: MOB kinase activator
Length: 184 amino acids
Theoretical weight: 21.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9H8S9 (Residues: 33-216; Coverage: 85%)
Sequence domains: Mob1/phocein family
Structure domains: MOB kinase activator
Non-structural protein 5A
Molecule details ›
Chains: E, F, G, H
Length: 20 amino acids
Theoretical weight: 2.4 KDa
Source organism: Hepatitis C virus JFH-1
Expression system: Not provided
UniProt:
Length: 20 amino acids
Theoretical weight: 2.4 KDa
Source organism: Hepatitis C virus JFH-1
Expression system: Not provided
UniProt:
- Canonical: Q99IB8 (Residues: 2284-2303; Coverage: 1%)
