4j2l

X-ray diffraction
3.15Å resolution

Crystal Structure of AXH domain complexed with Capicua

Released:

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-156966 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ataxin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P54253 (Residues: 562-688; Coverage: 16%)
Gene names: ATX1, ATXN1, SCA1
Sequence domains: Ataxin-1 and HBP1 module (AXH)
Protein capicua homolog Chains: C, D
Molecule details ›
Chains: C, D
Length: 28 amino acids
Theoretical weight: 3.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96RK0 (Residues: 21-48; Coverage: 2%)
Gene names: CIC, KIAA0306

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6B
Spacegroup: P4322
Unit cell:
a: 53.5Å b: 53.5Å c: 276.212Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.236 0.294
Expression system: Escherichia coli