› 4jan

X-ray diffraction
3.15Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212904 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Human immunodeficiency virus 1 envelope glycoprotein Gp120 domain-containing protein Chains: G, I
Molecule details ›
Chains: G, I
Length: 355 amino acids
Theoretical weight: 39.27 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: R4GRV3 (Residues: 1-355; Coverage: 100%)
Sequence domains: Envelope glycoprotein GP120
ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103 Chains: A, H
Molecule details ›
Chains: A, H
Length: 226 amino acids
Theoretical weight: 23.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103 Chains: B, L
Molecule details ›
Chains: B, L
Length: 209 amino acids
Theoretical weight: 22.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand NAG 10 x NAG
Ligand NA 2 x NA
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 48.943Å b: 208.651Å c: 69.422Å
α: 90° β: 107.21° γ: 90°
R-values:
R R work R free
0.199 0.196 0.256
Expression system: Homo sapiens

Quick links

Citations

188 review citations

Germinal Center B Cell Dynamics.
Mesin et al. (2016)
187 more

22 mentions without citation

Advances in structure-based vaccine design.
Kulp et al. (2013)
21 more